The maximal electroshock seizure (MES) model in the preclinical assessment of potential new antiepileptic drugs
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چکیده
منابع مشابه
The maximal electroshock seizure (MES) model in the preclinical assessment of potential new antiepileptic drugs.
The choice of appropriate animal models for the initial in vivo testing of potential anticonvulsant compounds is one of the most important steps in the successful search for new antiepileptic drugs. The purpose of this paper is to describe the most important aspects to take into account when performing the maximal electroshock seizure (MES) test in the routine laboratory screening of new antiep...
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ژورنال
عنوان ژورنال: Methods and Findings in Experimental and Clinical Pharmacology
سال: 2009
ISSN: 0379-0355
DOI: 10.1358/mf.2009.31.2.1338414